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Opposing Post-Translational Modifications Regulate Cep76 Function to Suppress Centriole Amplification

Centrioles are critical for many cellular processes including cell division and cilia assembly. The number of centrioles within a cell is under strict control, and deregulation of centriole copy number is a hallmark of cancer. The molecular mechanisms that halt centriole amplification have not been...

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Detalhes bibliográficos
Publicado no:Oncogene
Main Authors: Barbelanne, Marine, Chiu, Andrea, Qian, Jin, Tsang, William Y.
Formato: Artigo
Idioma:Inglês
Publicado em: 2016
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5125818/
https://ncbi.nlm.nih.gov/pubmed/27065328
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/onc.2016.74
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