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Genetic and epigenetic heterogeneity of epithelial ovarian cancer and the clinical implications for molecular targeted therapy

Epithelial ovarian cancer (EOC) is the most lethal gynaecological malignancy, and tumoural heterogeneity (TH) has been blamed for treatment failure. The genomic and epigenomic atlas of EOC varies significantly with tumour histotype, grade, stage, sensitivity to chemotherapy and prognosis. Rapidly ac...

詳細記述

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書誌詳細
出版年:J Cell Mol Med
主要な著者: Bai, Huimin, Cao, Dongyan, Yang, Jiaxin, Li, Menghui, Zhang, Zhenyu, Shen, Keng
フォーマット: Artigo
言語:Inglês
出版事項: John Wiley and Sons Inc. 2016
主題:
オンライン・アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC5125785/
https://ncbi.nlm.nih.gov/pubmed/26800494
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/jcmm.12771
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