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Proton transfer is rate-limiting for translocation of precursor proteins by the Escherichia coli translocase.

The protonmotive force stimulates translocation in vivo, in crude in vitro reactions, and in a purified, reconstituted reaction. Translocation activity is a function of the pH at the inner face of the membrane. Both the transmembrane pH gradient and the transmembrane electrical potential stimulate t...

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Veröffentlicht in:Proc Natl Acad Sci U S A
Hauptverfasser: Driessen, A J, Wickner, W
Format: Artigo
Sprache:Inglês
Veröffentlicht: National Academy of Sciences 1991
Schlagworte:
Online-Zugang:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC51254/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/1826054/
https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.88.6.2471
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