NOVEL EPIGENETIC CHANGES IN CDKN2A ARE ASSOCIATED WITH PROGRESSION OF CERVICAL INTRAEPITHELIAL NEOPLASIA

OBJECTIVE: To conduct a comprehensive mapping of the genomic DNA methylation in CDKN2A, which codes for the p16(INK4A) and p14(ARF) proteins, and 14 of the most promising DNA methylation marker candidates previously reported to be associated with progression of low-grade cervical intraepithelial neo...

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Publicat a:Gynecol Oncol
Autors principals: Wijetunga, N. Ari, Belbin, Thomas J., Burk, Robert D., Whitney, Kathleen, Abadi, Maria, Greally, John M., Einstein, Mark H., Schlecht, Nicolas F.
Format: Artigo
Idioma:Inglês
Publicat: 2016
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Article
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC5125392/
https://ncbi.nlm.nih.gov/pubmed/27401842
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.ygyno.2016.07.006
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