NOVEL EPIGENETIC CHANGES IN CDKN2A ARE ASSOCIATED WITH PROGRESSION OF CERVICAL INTRAEPITHELIAL NEOPLASIA

OBJECTIVE: To conduct a comprehensive mapping of the genomic DNA methylation in CDKN2A, which codes for the p16(INK4A) and p14(ARF) proteins, and 14 of the most promising DNA methylation marker candidates previously reported to be associated with progression of low-grade cervical intraepithelial neo...

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Publicado en:Gynecol Oncol
Autores principales: Wijetunga, N. Ari, Belbin, Thomas J., Burk, Robert D., Whitney, Kathleen, Abadi, Maria, Greally, John M., Einstein, Mark H., Schlecht, Nicolas F.
Formato: Artigo
Lenguaje:Inglês
Publicado: 2016
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Article
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC5125392/
https://ncbi.nlm.nih.gov/pubmed/27401842
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.ygyno.2016.07.006
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