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Knockdown of Decoy Receptor 3 Impairs Growth and Invasiveness of Hepatocellular Carcinoma Cell Line of HepG2

BACKGROUND: Decoy receptor 3 (DcR3) binds to Fas ligand (FasL) and inhibits FasL-induced apoptosis. The receptor is overexpressed in hepatocellular carcinoma (HCC), and it is associated with the growth and metastatic spread of tumors. DcR3 holds promises as a new target for the treatment of HCC, but...

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Bibliographische Detailangaben
Veröffentlicht in:Chin Med J (Engl)
Hauptverfasser: Zhou, Xiao-Na, Li, Guang-Ming, Xu, Ying-Chen, Zhao, Tuan-Jie, Wu, Ji-Xiang
Format: Artigo
Sprache:Inglês
Veröffentlicht: Medknow Publications & Media Pvt Ltd 2016
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5125343/
https://ncbi.nlm.nih.gov/pubmed/27779171
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4103/0366-6999.192775
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