Dendritic cell function and pathogen-specific T cell immunity are inhibited in mice administered levonorgestrel prior to intranasal Chlamydia trachomatis infection

The growing popularity of levonorgestrel (LNG)-releasing intra-uterine systems for long-acting reversible contraception provides strong impetus to define immunomodulatory properties of this exogenous progestin. In initial in vitro studies herein, we found LNG significantly impaired activation of hum...

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Bibliografiska uppgifter
I publikationen:Sci Rep
Huvudupphovsmän: Quispe Calla, Nirk E., Vicetti Miguel, Rodolfo D., Mei, Ao, Fan, Shumin, Gilmore, Jocelyn R., Cherpes, Thomas L.
Materialtyp: Artigo
Språk:Inglês
Publicerad: Nature Publishing Group 2016
Ämnen:
Article
Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC5125275/
https://ncbi.nlm.nih.gov/pubmed/27892938
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/srep37723
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