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New Genome-Wide Algorithm Identifies Novel In-Vivo Expressed Mycobacterium Tuberculosis Antigens Inducing Human T-Cell Responses with Classical and Unconventional Cytokine Profiles

New strategies are needed to develop better tools to control TB, including identification of novel antigens for vaccination. Such Mtb antigens must be expressed during Mtb infection in the major target organ, the lung, and must be capable of eliciting human immune responses. Using genome-wide transc...

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Λεπτομέρειες βιβλιογραφικής εγγραφής
Τόπος έκδοσης:Sci Rep
Κύριοι συγγραφείς: Coppola, Mariateresa, van Meijgaarden, Krista E., Franken, Kees L. M. C., Commandeur, Susanna, Dolganov, Gregory, Kramnik, Igor, Schoolnik, Gary K., Comas, Inaki, Lund, Ole, Prins, Corine, van den Eeden, Susan J. F., Korsvold, Gro E., Oftung, Fredrik, Geluk, Annemieke, Ottenhoff, Tom H. M.
Μορφή: Artigo
Γλώσσα:Inglês
Έκδοση: Nature Publishing Group 2016
Θέματα:
Διαθέσιμο Online:https://ncbi.nlm.nih.gov/pmc/articles/PMC5125271/
https://ncbi.nlm.nih.gov/pubmed/27892960
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/srep37793
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