A randomized and blinded comparison of qPCR and NGS-based detection of aneuploidy in a cell line mixture model of blastocyst biopsy mosaicism

PURPOSE: A subset of preimplantation stage embryos may possess mosaicism of chromosomal constitution, representing a possible limitation to the clinical predictive value of comprehensive chromosome screening (CCS) from a single biopsy. However, contemporary methods of CCS may be capable of predictin...

Täydet tiedot

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Bibliografiset tiedot
Julkaisussa:J Assist Reprod Genet
Päätekijät: Goodrich, David, Tao, Xin, Bohrer, Chelsea, Lonczak, Agnieszka, Xing, Tongji, Zimmerman, Rebekah, Zhan, Yiping, Scott Jr, Richard T., Treff, Nathan R.
Aineistotyyppi: Artigo
Kieli:Inglês
Julkaistu: Springer US 2016
Aiheet:
Genetics
Linkit:https://ncbi.nlm.nih.gov/pmc/articles/PMC5125146/
https://ncbi.nlm.nih.gov/pubmed/27497716
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s10815-016-0784-3
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