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Crystal structures of translocator protein (TSPO) and mutant mimic of a human polymorphism
The 18-kilodalton translocator protein (TSPO), proposed to be a key player in cholesterol transport into mitochondria, is highly expressed in steroidogenic tissues, metastatic cancer, and inflammatory and neurological diseases such as Alzheimer’s and Parkinson’s. TSPO ligands, including benzodiazepi...
Shranjeno v:
| izdano v: | Science |
|---|---|
| Main Authors: | , , , , |
| Format: | Artigo |
| Jezik: | Inglês |
| Izdano: |
2015
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| Teme: | |
| Online dostop: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5125025/ https://ncbi.nlm.nih.gov/pubmed/25635101 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1126/science.1260590 |
| Oznake: |
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