Sensitization with vaccinia virus encoding H5N1 hemagglutinin restores immune potential against H5N1 influenza virus

H5N1 highly pathogenic avian influenza (H5N1 HPAI) virus causes elevated mortality compared with seasonal influenza viruses like H1N1 pandemic influenza (H1N1 pdm) virus. We identified a mechanism associated with the severe symptoms seen with H5N1 HPAI virus infection. H5N1 HPAI virus infection indu...

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Pubblicato in:Sci Rep
Autori principali: Yasui, Fumihiko, Itoh, Yasushi, Ikejiri, Ai, Kitabatake, Masahiro, Sakaguchi, Nobuo, Munekata, Keisuke, Shichinohe, Shintaro, Hayashi, Yukiko, Ishigaki, Hirohito, Nakayama, Misako, Sakoda, Yoshihiro, Kida, Hiroshi, Ogasawara, Kazumasa, Kohara, Michinori
Natura: Artigo
Lingua:Inglês
Pubblicazione: Nature Publishing Group 2016
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Article
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC5124960/
https://ncbi.nlm.nih.gov/pubmed/27892498
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/srep37915
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