Sphingomyelin generated by sphingomyelin synthase 1 is involved in attachment and infection with Japanese encephalitis virus

Japanese encephalitis virus (JEV) is a mosquito-borne RNA virus which infects target cells via the envelope protein JEV-E. However, its cellular targets are largely unknown. To investigate the role of sphingomyelin (SM) in JEV infection, we utilized SM-deficient immortalized mouse embryonic fibrobla...

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Published in:Sci Rep
Main Authors: Taniguchi, Makoto, Tasaki, Takafumi, Ninomiya, Hideaki, Ueda, Yoshibumi, Kuremoto, Koh-ichi, Mitsutake, Susumu, Igarashi, Yasuyuki, Okazaki, Toshiro, Takegami, Tsutomu
Format: Artigo
Language:Inglês
Published: Nature Publishing Group 2016
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Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC5124946/
https://ncbi.nlm.nih.gov/pubmed/27892528
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/srep37829
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