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Transition steps in peroxide reduction and a molecular switch for peroxide robustness of prokaryotic peroxiredoxins

In addition to their antioxidant function, the eukaryotic peroxiredoxins (Prxs) facilitate peroxide-mediated signaling by undergoing controlled inactivation by peroxide-driven over-oxidation. In general, the bacterial enzyme lacks this controlled inactivation mechanism, making it more resistant to h...

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Bibliografische gegevens
Gepubliceerd in:Sci Rep
Hoofdauteurs: Kamariah, Neelagandan, Sek, Mun Foong, Eisenhaber, Birgit, Eisenhaber, Frank, Grüber, Gerhard
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: Nature Publishing Group 2016
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Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5124861/
https://ncbi.nlm.nih.gov/pubmed/27892488
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/srep37610
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