18α-Glycyrrhetinic Acid Proteasome Activator Decelerates Aging and Alzheimer's Disease Progression in Caenorhabditis elegans and Neuronal Cultures

Aims: Proteasomes are constituents of the cellular proteolytic networks that maintain protein homeostasis through regulated proteolysis of normal and abnormal (in any way) proteins. Genetically mediated proteasome activation in multicellular organisms has been shown to promote longevity and to exert...

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Vydáno v:Antioxid Redox Signal
Hlavní autoři: Papaevgeniou, Nikoletta, Sakellari, Marianthi, Jha, Sweta, Tavernarakis, Nektarios, Holmberg, Carina I., Gonos, Efstathios S., Chondrogianni, Niki
Médium: Artigo
Jazyk:Inglês
Vydáno: Mary Ann Liebert, Inc. 2016
Témata:
Forum Original Research CommunicationsProteasome (T. Grune, Ed.)
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC5124744/
https://ncbi.nlm.nih.gov/pubmed/26886723
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1089/ars.2015.6494
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