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Calciseptine, a peptide isolated from black mamba venom, is a specific blocker of the L-type calcium channel.

The venom of the black mamba contains a 60-amino acid peptide called calciseptine. The peptide has been fully sequenced. It is a smooth muscle relaxant and an inhibitor of cardiac contractions. Its physiological action resembles that of drugs, such as the 1,4-dihydropyridines, which are important in...

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Detalhes bibliográficos
Main Authors: de Weille, J R, Schweitz, H, Maes, P, Tartar, A, Lazdunski, M
Formato: Artigo
Idioma:Inglês
Publicado em: 1991
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC51247/
https://ncbi.nlm.nih.gov/pubmed/1848702
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