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Specifying a target trial prevents immortal time bias and other self-inflicted injuries in observational analyses

Many analyses of observational data are attempts to emulate a target trial. The emulation of the target trial may fail when researchers deviate from simple principles that guide the design and analysis of randomized experiments. We review a framework to describe and prevent biases, including immorta...

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Detalles Bibliográficos
Publicado en:J Clin Epidemiol
Autores principales: Hernán, Miguel A., Sauer, Brian C., Hernández-Díaz, Sonia, Platt, Robert, Shrier, Ian
Formato: Artigo
Lenguaje:Inglês
Publicado: 2016
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Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC5124536/
https://ncbi.nlm.nih.gov/pubmed/27237061
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jclinepi.2016.04.014
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