Serotonin engages an anxiety and fear-promoting circuit in the extended amygdala

Serotonin (5-hydroxytryptamine; 5-HT) is a neurotransmitter that has an essential role in the regulation of emotion. The precise circuits through which aversive states are orchestrated by 5-HT, however, have not yet been defined. Here we show that 5-HT from the dorsal raphe nucleus (5-HT(DRN)) enhan...

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Published in:Nature
Main Authors: Marcinkiewcz, Catherine A., Mazzone, Christopher M., D’Agostino, Giuseppe, Halladay, Lindsay R., Hardaway, J. Andrew, DiBerto, Jeffrey F., Navarro, Montserrat, Burnham, Nathan, Cristiano, Claudia, Dorrier, Cayce E., Tipton, Gregory J., Ramakrishnan, Charu, Kozicz, Tamas, Deisseroth, Karl, Thiele, Todd E., McElligott, Zoe A., Holmes, Andrew, Heisler, Lora K., Kash, Thomas L.
Format: Artigo
Language:Inglês
Published: 2016
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Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC5124365/
https://ncbi.nlm.nih.gov/pubmed/27556938
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/nature19318
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