Co-infusion of haplo-identical CD19-chimeric antigen receptor T cells and stem cells achieved full donor engraftment in refractory acute lymphoblastic leukemia

BACKGROUND: Elderly patients with relapsed and refractory acute lymphoblastic leukemia (ALL) have poor prognosis. Autologous CD19 chimeric antigen receptor-modified T (CAR-T) cells have potentials to cure patients with B cell ALL; however, safety and efficacy of allogeneic CD19 CAR-T cells are still...

Πλήρης περιγραφή

Αποθηκεύτηκε σε:
Λεπτομέρειες βιβλιογραφικής εγγραφής
Τόπος έκδοσης:J Hematol Oncol
Κύριοι συγγραφείς: Cai, Bo, Guo, Mei, Wang, Yao, Zhang, Yajing, Yang, Jun, Guo, Yelei, Dai, Hanren, Yu, Changlin, Sun, Qiyun, Qiao, Jianhui, Hu, Kaixun, Zuo, Hongli, Dong, Zheng, Zhang, Zechuan, Feng, Mingxing, Li, Bingxia, Sun, Yujing, Liu, Tieqiang, Liu, Zhiqing, Wang, Yi, Huang, Yajing, Yao, Bo, Han, Weidong, Ai, Huisheng
Μορφή: Artigo
Γλώσσα:Inglês
Έκδοση: BioMed Central 2016
Θέματα:
Case Report
Διαθέσιμο Online:https://ncbi.nlm.nih.gov/pmc/articles/PMC5124292/
https://ncbi.nlm.nih.gov/pubmed/27887660
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s13045-016-0357-z
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