Dynamic simulations show repeated narrowing maximizes DNA linearization in elastomeric nanochannels

This paper uses computer simulations to reveal unprecedented details about linearization of deoxyribonucleic acid (DNA) inside dynamic nanochannels that can be repeatedly widened and narrowed. We first analyze the effect of rate of channel narrowing on DNA linearization dynamics. Quick (∼0.1 s) narr...

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Shranjeno v:
Bibliografske podrobnosti
izdano v:Biomicrofluidics
Main Authors: Han, Minsub, Kim, Byoung Choul, Matsuoka, Toshiki, Thouless, M. D., Takayama, Shuichi
Format: Artigo
Jezik:Inglês
Izdano: AIP Publishing LLC 2016
Teme:
Regular Articles
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC5123996/
https://ncbi.nlm.nih.gov/pubmed/27965731
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1063/1.4967963
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