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3-Hydroxybutyrate Regulates Energy Metabolism and Induces BDNF Expression in Cerebral Cortical Neurons

During fasting and vigorous exercise, a shift of brain cell energy substrate utilization from glucose to the ketone 3-hydroxybutyrate (3OHB) occurs. Studies have shown that 3OHB can protect neurons against excitotoxicity and oxidative stress, but the underlying mechanisms are unclear. Neurons mainta...

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Detalhes bibliográficos
Publicado no:J Neurochem
Main Authors: Marosi, Krisztina, Kim, Sang Woo, Moehl, Keelin, Scheibye-Knudsen, Morten, Cheng, Aiwu, Cutler, Roy, Camandola, Simonetta, Mattson, Mark P.
Formato: Artigo
Idioma:Inglês
Publicado em: 2016
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5123937/
https://ncbi.nlm.nih.gov/pubmed/27739595
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/jnc.13868
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