Characterization of a trypsin-dependent avian influenza H5N1-pseudotyped HIV vector system for high throughput screening of inhibitory molecules

In this study, we have generated and characterized an avian influenza H5N1 hemagglutinin (HA), neuraminidase (NA) and M2 ion channel pseudotyped HIV-based vector system (HaNaM-pseudotyped HIV vector). The cleavage site of the HA protein was modified to necessitate trypsin-dependent maturation of the...

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Detalhes bibliográficos
Publicado no:Antiviral Res
Main Authors: Ao, Zhujun, Patel, Ami, Tran, Kaylie, He, Xinying, Fowke, Keith, Coombs, Kevin, Kobasa, Darwyn, Kobinger, Gary, Yao, Xiaojian
Formato: Artigo
Idioma:Inglês
Publicado em: 2008
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5123875/
https://ncbi.nlm.nih.gov/pubmed/18359097
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.antiviral.2008.02.001
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