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HIF-1α Mediates Increased Sympathoexcitation via Glutamatergic NMDA Receptors in the PVN of Rats with Chronic Heart Failure
BACKGROUND: Increased sympathetic outflow is a major contributor to the progression of chronic heart failure (CHF). Potentiation of glutamatergic tone has been causally related to the sympathoexcitation in CHF. Specifically, an increase in the N-methyl-D-aspartate-type1 receptor (NMDA-NR(1)) express...
Gardado en:
| Publicado en: | Circ Heart Fail |
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| Main Authors: | , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado: |
2016
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| Assuntos: | |
| Acceso en liña: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5123857/ https://ncbi.nlm.nih.gov/pubmed/27810863 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1161/CIRCHEARTFAILURE.116.003423 |
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