Isolation of human trophoblastic extracellular vesicles and characterization of their cargo and antiviral activity

INTRODUCTION: Primary human trophoblasts release a repertoire of extracellular vesicles (EVs). Among them are nano-sized exosomes, which we found to suppress the replication of a wide range of diverse viruses. These exosomes contain trophoblastic microRNAs (miRNAs) that are expressed from the chromo...

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Détails bibliographiques
Publié dans:Placenta
Auteurs principaux: Ouyang, Yingshi, Bayer, Avraham, Chu, Tianjiao, Tyurin, Vladimir A., Kagan, Valerian E., Morelli, Adrian E., Coyne, Carolyn B, Sadovsky, Yoel
Format: Artigo
Langue:Inglês
Publié: 2016
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Article
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC5123854/
https://ncbi.nlm.nih.gov/pubmed/27780544
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.placenta.2016.09.008
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