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Step-wise loss of antidepressant effectiveness with repeated antidepressant trials in bipolar II depression

OBJECTIVE: This study examined the relationship between the number of prior antidepressant treatment trials and step-wise increase in pharmacodynamic tolerance (or progressive loss of effectiveness) in subjects with bipolar II depression. METHODS: Subjects ≥ 18 years old with bipolar II depression (...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Veröffentlicht in:Bipolar Disord
Hauptverfasser: Amsterdam, Jay D, Lorenzo-Luaces, Lorenzo, DeRubeis, Robert J
Format: Artigo
Sprache:Inglês
Veröffentlicht: 2016
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5123793/
https://ncbi.nlm.nih.gov/pubmed/27805299
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/bdi.12442
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