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Step-wise loss of antidepressant effectiveness with repeated antidepressant trials in bipolar II depression
OBJECTIVE: This study examined the relationship between the number of prior antidepressant treatment trials and step-wise increase in pharmacodynamic tolerance (or progressive loss of effectiveness) in subjects with bipolar II depression. METHODS: Subjects ≥ 18 years old with bipolar II depression (...
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| Published in: | Bipolar Disord |
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| Main Authors: | , , |
| Format: | Artigo |
| Language: | Inglês |
| Published: |
2016
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| Subjects: | |
| Online Access: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5123793/ https://ncbi.nlm.nih.gov/pubmed/27805299 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/bdi.12442 |
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