Aspirin inhibits interleukin 1-induced prostaglandin H synthase expression in cultured endothelial cells.
Prostaglandin H (PGH) synthase (EC 1.14.99.1) is a key enzyme in the biosynthesis of prostaglandins, thromboxane, and prostacyclin. In cultured human umbilical vein endothelial cells, interleukin 1 (IL-1) is known to induce the synthesis of this enzyme, thereby raising the level of PGH synthase prot...
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| Publicado no: | Proc Natl Acad Sci U S A |
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| Principais autores: | , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
National Academy of Sciences
1991
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC51236/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/1900943/ https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.88.6.2384 |
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