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HPV16 integration probably contributes to cervical oncogenesis through interrupting tumor suppressor genes and inducing chromosome instability

BACKGROUND: The integration of human papilloma virus (HPV) into host genome is one of the critical steps that lead to the progression of precancerous lesion into cancer. However, the mechanisms and consequences of such integration events are poorly understood. This study aims to explore those questi...

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Detalhes bibliográficos
Publicado no:J Exp Clin Cancer Res
Main Authors: Zhao, Jun-Wei, Fang, Fang, Guo, Yi, Zhu, Tai-Lin, Yu, Yun-Yun, Kong, Fan-Fei, Han, Ling-Fei, Chen, Dong-Sheng, Li, Fang
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2016
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5123399/
https://ncbi.nlm.nih.gov/pubmed/27884161
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s13046-016-0454-4
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