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Soluble IL-33 receptor sST2 inhibits colorectal cancer malignant growth by modifying the tumour microenvironment

Interleukin-33 (IL-33) was recently shown to be involved in the inflammatory tumour microenvironment and the progression of colorectal cancer (CRC). We report here that the expression level of sST2, a soluble form of the IL-33 receptor (ST2L), is inversely associated with the malignant growth of CRC...

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Detalhes bibliográficos
Publicado no:Nat Commun
Main Authors: Akimoto, Miho, Maruyama, Riruke, Takamaru, Hiroyuki, Ochiya, Takahiro, Takenaga, Keizo
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group 2016
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5123057/
https://ncbi.nlm.nih.gov/pubmed/27882929
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/ncomms13589
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