Neutralization mechanism of a highly potent antibody against Zika virus

The rapid spread of Zika virus (ZIKV), which causes microcephaly and Guillain-Barré syndrome, signals an urgency to identify therapeutics. Recent efforts to rescreen dengue virus human antibodies for ZIKV cross-neutralization activity showed antibody C10 as one of the most potent. To investigate the...

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Veröffentlicht in:Nat Commun
Hauptverfasser: Zhang, Shuijun, Kostyuchenko, Victor A., Ng, Thiam-Seng, Lim, Xin-Ni, Ooi, Justin S. G., Lambert, Sebastian, Tan, Ter Yong, Widman, Douglas G., Shi, Jian, Baric, Ralph S., Lok, Shee-Mei
Format: Artigo
Sprache:Inglês
Veröffentlicht: Nature Publishing Group 2016
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Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5123051/
https://ncbi.nlm.nih.gov/pubmed/27882950
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/ncomms13679
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