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Unlocking sperm chromatin at fertilization requires a dedicated egg thioredoxin in Drosophila

In most animals, the extreme compaction of sperm DNA is achieved after the massive replacement of histones with sperm nuclear basic proteins (SNBPs), such as protamines. In some species, the ultracompact sperm chromatin is stabilized by a network of disulfide bonds connecting cysteine residues prese...

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Detalhes bibliográficos
Publicado no:Nat Commun
Main Authors: Tirmarche, Samantha, Kimura, Shuhei, Dubruille, Raphaëlle, Horard, Béatrice, Loppin, Benjamin
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group 2016
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5122968/
https://ncbi.nlm.nih.gov/pubmed/27876811
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/ncomms13539
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