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Elevated expression of MMP-13 and TIMP-1 in head and neck squamous cell carcinomas may reflect increased tumor invasiveness

BACKGROUND: Matrix metalloproteinases [MMPs], which degrade the extracellular matrix, play an important role in the invasion and metastasis of squamous cell carcinomas. One MMP, MMP-13, is thought to play a central role in MMP activation. The purpose of this study was to investigate MMP-13 and TIMP-...

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Autori principali: Culhaci, Nil, Metin, Kubilay, Copcu, Eray, Dikicioglu, Emel
Natura: Artigo
Lingua:Inglês
Pubblicazione: BioMed Central 2004
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC512290/
https://ncbi.nlm.nih.gov/pubmed/15291964
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1471-2407-4-42
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