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Impairment of PDGF-induced chemotaxis by extracellular α-synuclein through selective inhibition of Rac1 activation
Parkinson’s disease (PD) is characterized by α-synuclein (α-Syn)-positive intracytoplasmic inclusions, known as Lewy bodies. Although it is known that extracellular α-Syn is detected in the plasma and cerebrospinal fluid, its physiological significance remains unclear. Here, we show that extracellul...
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| Pubblicato in: | Sci Rep |
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| Autori principali: | , , , , , |
| Natura: | Artigo |
| Lingua: | Inglês |
| Pubblicazione: |
Nature Publishing Group
2016
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| Soggetti: | |
| Accesso online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5122898/ https://ncbi.nlm.nih.gov/pubmed/27886249 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/srep37810 |
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