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Hyperbaric Oxygen Pretreatment Improves Cognition and Reduces Hippocampal Damage Via p38 Mitogen-Activated Protein Kinase in a Rat Model

PURPOSE: To investigate the effects of hyperbaric oxygen (HBO) pretreatment on cognitive decline and neuronal damage in an Alzheimer’s disease (AD) rat model. MATERIALS AND METHODS: Rats were divided into three groups: normal saline (NS), AD, and HBO+AD. In the AD group, amyloid β peptide (Aβ)(1-40)...

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Bibliographic Details
Published in:Yonsei Med J
Main Authors: Zhao, Baisong, Pan, Yongying, Wang, Zixin, Xu, Haiping, Song, Xingrong
Format: Artigo
Language:Inglês
Published: Yonsei University College of Medicine 2017
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Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC5122628/
https://ncbi.nlm.nih.gov/pubmed/27873505
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3349/ymj.2017.58.1.131
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