Loss of GFAT1 promotes epithelial-to-mesenchymal transition and predicts unfavorable prognosis in gastric cancer

Gastric cancer remains the third leading cause of cancer-related mortality worldwide, and invasion and metastasis of gastric cancer represent the major reason for its poor prognosis. Glutamine: fructose-6-phosphate amidotransferase 1 (GFAT1) is the first and rate-limiting enzyme of hexosamine biosyn...

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Dettagli Bibliografici
Pubblicato in:Oncotarget
Autori principali: Duan, Fangfang, Jia, Dongwei, Zhao, Junjie, Wu, Weicheng, Min, Lingqiang, Song, Shushu, Wu, Hao, Wang, Lan, Wang, Hongshan, Ruan, Yuanyuan, Gu, Jianxin
Natura: Artigo
Lingua:Inglês
Pubblicazione: Impact Journals LLC 2016
Soggetti:
Research Paper
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC5122401/
https://ncbi.nlm.nih.gov/pubmed/27509259
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.18632/oncotarget.9538
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