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DNA demethylating agent decitabine broadens the peripheral T cell receptor repertoire
PURPOSE: Decitabine, a promising epi-immunotherapeutic agent has shown clinical responses in solid tumor patients, while the anti-tumor mechanisms were unclear. We aimed to investigate the immunomodulatory effect of decitabine in peripheral T cells. EXPERIMENTAL DESIGN: We applied next-generation se...
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| Publicado no: | Oncotarget |
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| Principais autores: | , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Impact Journals LLC
2016
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5122357/ https://ncbi.nlm.nih.gov/pubmed/27191266 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.18632/oncotarget.9352 |
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