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c-Src/Cav1-dependent activation of the EGFR by Dsg2

The desmosomal cadherin, desmoglein 2 (Dsg2), is deregulated in a variety of human cancers including those of the skin. When ectopically expressed in the epidermis of transgenic mice, Dsg2 activates multiple mitogenic signaling pathways and increases susceptibility to tumorigenesis. However, the mol...

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Dettagli Bibliografici
Pubblicato in:Oncotarget
Autori principali: Overmiller, Andrew M., McGuinn, Kathleen P., Roberts, Brett J., Cooper, Felicia, Brennan-Crispi, Donna M., Deguchi, Takahiro, Peltonen, Sirkku, James K., Wahl, Mahoney, M? G.
Natura: Artigo
Lingua:Inglês
Pubblicazione: Impact Journals LLC 2016
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC5122330/
https://ncbi.nlm.nih.gov/pubmed/26918609
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.18632/oncotarget.7675
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