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Measuring intratumor heterogeneity by network entropy using RNA-seq data

Intratumor heterogeneity (ITH) is observed at different stages of tumor progression, metastasis and reouccurence, which can be important for clinical applications. We used RNA-sequencing data from tumor samples, and measured the level of ITH in terms of biological network states. To model complex re...

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Detalhes bibliográficos
Publicado no:Sci Rep
Main Authors: Park, Youngjune, Lim, Sangsoo, Nam, Jin-Wu, Kim, Sun
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group 2016
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5121893/
https://ncbi.nlm.nih.gov/pubmed/27883053
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/srep37767
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