Anti-high mobility group box-1 (HMGB1) antibody attenuates delayed cerebral vasospasm and brain injury after subarachnoid hemorrhage in rats

Although delayed cerebral vasospasm (DCV) following subarachnoid hemorrhage (SAH) is closely related to the progression of brain damage, little is known about the molecular mechanism underlying its development. High mobility group box-1 (HMGB1) plays an important role as an initial inflammatory medi...

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Udgivet i:Sci Rep
Main Authors: Haruma, Jun, Teshigawara, Kiyoshi, Hishikawa, Tomohito, Wang, Dengli, Liu, Keyue, Wake, Hidenori, Mori, Shuji, Takahashi, Hideo Kohka, Sugiu, Kenji, Date, Isao, Nishibori, Masahiro
Format: Artigo
Sprog:Inglês
Udgivet: Nature Publishing Group 2016
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Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5121891/
https://ncbi.nlm.nih.gov/pubmed/27883038
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/srep37755
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