Straight and paired helical filaments in Alzheimer disease have a common structural unit.
The presence of abundant neurofibrillary tangles in certain areas of the brain constitutes one of the defining pathological characteristics of Alzheimer disease. The predominant component of the tangle is an abnormal fibrous assembly known as the paired helical filament (PHF). The PHF is formed by a...
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| Publicado no: | Proc Natl Acad Sci U S A |
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| Autor principal: | |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
National Academy of Sciences
1991
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC51216/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/1706519/ https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.88.6.2288 |
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