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Signatures of natural selection on genetic variants affecting complex human traits()

It has recently been hypothesized that polygenic adaptation, resulting in modest allele frequency changes at many loci, could be a major mechanism behind the adaptation of complex phenotypes in human populations. Here we leverage the large number of variants that have been identified through genome-...

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Publicado en:Appl Transl Genom
Main Authors: Zhang, Ge, Muglia, Louis J., Chakraborty, Ranajit, Akey, Joshua M., Williams, Scott M.
Formato: Artigo
Idioma:Inglês
Publicado: Elsevier 2013
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC5121263/
https://ncbi.nlm.nih.gov/pubmed/27896059
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.atg.2013.10.002
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