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Low Volume Resuscitation Using Polyethylene Glycol-20k in a Pre-Clinical Porcine Model of Hemorrhagic Shock

INTRODUCTION: Polyethylene glycol-20k (PEG-20k) is highly effective for low volume resuscitation (LVR) by increasing tolerance to the low volume state. In our rodent shock model, PEG-20k increased survival and expanded the “golden hour” 16-fold compared to saline. The molecular mechanism is largely...

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Detalhes bibliográficos
Publicado no:J Trauma Acute Care Surg
Main Authors: Plant, Valerie, Limkemann, Ashley, Liebrecht, Loren, Blocher, Charles, Ferrada, Paula, Aboutanos, Michel, Mangino, Martin J.
Formato: Artigo
Idioma:Inglês
Publicado em: 2016
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5121040/
https://ncbi.nlm.nih.gov/pubmed/27280940
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1097/TA.0000000000001155
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