Genome-wide association studies of autoimmune vitiligo identify 23 new risk loci and highlight key pathways and regulatory variants

Vitiligo is an autoimmune disease in which depigmented skin results from destruction of melanocytes(1), with epidemiologic association with other autoimmune diseases(2). In previous linkage and genome-wide association studies (GWAS1, GWAS2), we identified 27 vitiligo susceptibility loci in patients...

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Publicado no:Nat Genet
Main Authors: Jin, Ying, Andersen, Genevieve, Yorgov, Daniel, Ferrara, Tracey M, Ben, Songtao, Brownson, Kelly M, Holland, Paulene J, Birlea, Stanca A, Siebert, Janet, Hartmann, Anke, Lienert, Anne, van Geel, Nanja, Lambert, Jo, Luiten, Rosalie M, Wolkerstorfer, Albert, van der Veen, JP Wietze, Bennett, Dorothy C, Taïeb, Alain, Ezzedine, Khaled, Kemp, E Helen, Gawkrodger, David J, Weetman, Anthony P, Kõks, Sulev, Prans, Ele, Kingo, Külli, Karelson, Maire, Wallace, Margaret R, McCormack, Wayne T, Overbeck, Andreas, Moretti, Silvia, Colucci, Roberta, Picardo, Mauro, Silverberg, Nanette B, Olsson, Mats, Valle, Yan, Korobko, Igor, Böhm, Markus, Lim, Henry W., Hamzavi, Iltefat, Zhou, Li, Mi, Qing-Sheng, Fain, Pamela R., Santorico, Stephanie A, Spritz, Richard A
Formato: Artigo
Idioma:Inglês
Publicado em: 2016
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5120758/
https://ncbi.nlm.nih.gov/pubmed/27723757
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/ng.3680
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