Somatic mutations of isocitrate dehydrogenases 1 and 2 are prognostic and follow-up markers in patients with acute myeloid leukaemia with normal karyotype

BACKGROUND: Mutations in the isocitrate dehydrogenase 1 and 2 (IDH1 and IDH2) genes are frequent molecular lesions in acute myeloid leukaemia with normal karyotype (AML-NK). The effects of IDH mutations on clinical features and treatment outcome in AML-NK have been widely investigated, but only a fe...

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Udgivet i:Radiol Oncol
Main Authors: Virijevic, Marijana, Karan-Djurasevic, Teodora, Marjanovic, Irena, Tosic, Natasa, Mitrovic, Mirjana, Djunic, Irena, Colovic, Natasa, Vidovic, Ana, Suvajdzic-Vukovic, Nada, Tomin, Dragica, Pavlovic, Sonja
Format: Artigo
Sprog:Inglês
Udgivet: De Gruyter 2016
Fag:
Research Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5120579/
https://ncbi.nlm.nih.gov/pubmed/27904446
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1515/raon-2016-0044
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