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Mendelian inheritance of trimodal CpG methylation sites suggests distal cis-acting genetic effects

BACKGROUND: Environmentally influenced phenotypes, such as obesity and insulin resistance, can be transmitted over multiple generations. Epigenetic modifications, such as methylation of DNA cytosine-guanine (CpG) pairs, may be carriers of inherited information. At the population level, the methylati...

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Detalhes bibliográficos
Publicado no:Clin Epigenetics
Main Authors: Zaghlool, Shaza B., Al-Shafai, Mashael, Al Muftah, Wadha A., Kumar, Pankaj, Gieger, Christian, Waldenberger, Melanie, Falchi, Mario, Suhre, Karsten
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2016
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5120560/
https://ncbi.nlm.nih.gov/pubmed/27895808
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s13148-016-0295-1
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