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Nuclear envelope structural defect underlies the main cause of aneuploidy in ovarian carcinogenesis
BACKGROUND: The Cancer Atlas project has shown that p53 is the only commonly (96 %) mutated gene found in high-grade serous epithelial ovarian cancer, the major histological subtype. Another general genetic change is extensive aneuploidy caused by chromosomal numerical instability, which is thought...
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| Veröffentlicht in: | BMC Cell Biol |
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| Hauptverfasser: | , , , |
| Format: | Artigo |
| Sprache: | Inglês |
| Veröffentlicht: |
BioMed Central
2016
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| Schlagworte: | |
| Online Zugang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5120486/ https://ncbi.nlm.nih.gov/pubmed/27875985 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12860-016-0114-8 |
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