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Nitric oxide has contrasting age-dependent effects on the functionality of murine hematopoietic stem cells

BACKGROUND: The success of hematopoietic stem cell (HSC) transplantation is dependent on the quality of the donor HSCs. Some sources of HSCs display reduced engraftment efficiency either because of inadequate number (e.g., fetal liver and cord blood), or age-related dysfunction (e.g. in older indivi...

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Bibliografiske detaljer
Udgivet i:Stem Cell Res Ther
Main Authors: Jalnapurkar, Sapana, Singh, Shweta, Devi, Moirangthem Ranjita, Limaye, Lalita, Kale, Vaijayanti
Format: Artigo
Sprog:Inglês
Udgivet: BioMed Central 2016
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5120451/
https://ncbi.nlm.nih.gov/pubmed/27876094
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s13287-016-0433-x
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