NF-kappaΒ-inducing kinase regulates stem cell phenotype in breast cancer

Breast cancer stem cells (BCSCs) overexpress components of the Nuclear factor-kappa B (NF-κB) signaling cascade and consequently display high NF-κB activity levels. Breast cancer cell lines with high proportion of CSCs exhibit high NF-κB-inducing kinase (NIK) expression. The role of NIK in the pheno...

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Pubblicato in:Sci Rep
Autori principali: Vazquez-Santillan, Karla, Melendez-Zajgla, Jorge, Jimenez-Hernandez, Luis Enrique, Gaytan-Cervantes, Javier, Muñoz-Galindo, Laura, Piña-Sanchez, Patricia, Martinez-Ruiz, Gustavo, Torres, Javier, Garcia-Lopez, Patricia, Gonzalez-Torres, Carolina, Ruiz, Victor, Avila-Moreno, Federico, Velasco-Velazquez, Marco, Perez-Tapia, Mayra, Maldonado, Vilma
Natura: Artigo
Lingua:Inglês
Pubblicazione: Nature Publishing Group 2016
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Article
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC5120353/
https://ncbi.nlm.nih.gov/pubmed/27876836
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/srep37340
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