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BGRMI: A method for inferring gene regulatory networks from time-course gene expression data and its application in breast cancer research

Reconstructing gene regulatory networks (GRNs) from gene expression data is a challenging problem. Existing GRN reconstruction algorithms can be broadly divided into model-free and model–based methods. Typically, model-free methods have high accuracy but are computation intensive whereas model-based...

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Detalhes bibliográficos
Publicado no:Sci Rep
Main Authors: Iglesias-Martinez, Luis F., Kolch, Walter, Santra, Tapesh
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group 2016
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5120305/
https://ncbi.nlm.nih.gov/pubmed/27876826
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/srep37140
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