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Positive and strongly relaxed purifying selection drive the evolution of repeats in proteins

Protein repeats are considered hotspots of protein evolution, associated with acquisition of new functions and novel phenotypic traits, including disease. Paradoxically, however, repeats are often strongly conserved through long spans of evolution. To resolve this conundrum, it is necessary to direc...

Täydet tiedot

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Bibliografiset tiedot
Julkaisussa:Nat Commun
Päätekijät: Persi, Erez, Wolf, Yuri I., Koonin, Eugene V
Aineistotyyppi: Artigo
Kieli:Inglês
Julkaistu: Nature Publishing Group 2016
Aiheet:
Linkit:https://ncbi.nlm.nih.gov/pmc/articles/PMC5120217/
https://ncbi.nlm.nih.gov/pubmed/27857066
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/ncomms13570
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