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In Vivo Expression of Reprogramming Factors Increases Hippocampal Neurogenesis and Synaptic Plasticity in Chronic Hypoxic-Ischemic Brain Injury

Neurogenesis and synaptic plasticity can be stimulated in vivo in the brain. In this study, we hypothesized that in vivo expression of reprogramming factors such as Klf4, Sox2, Oct4, and c-Myc would facilitate endogenous neurogenesis and functional recovery. CD-1® mice were induced at 1 week of age...

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Bibliografski detalji
Izdano u:Neural Plast
Glavni autori: Wi, Soohyun, Yu, Ji Hea, Kim, MinGi, Cho, Sung-Rae
Format: Artigo
Jezik:Inglês
Izdano: Hindawi Publishing Corporation 2016
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Online pristup:https://ncbi.nlm.nih.gov/pmc/articles/PMC5120183/
https://ncbi.nlm.nih.gov/pubmed/27900211
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1155/2016/2580837
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