Role of oxidative stress in oxaliplatin‐induced enteric neuropathy and colonic dysmotility in mice

BACKGROUND AND PURPOSE: Oxaliplatin is a platinum‐based chemotherapeutic drug used as a first‐line therapy for colorectal cancer. However, its use is associated with severe gastrointestinal side‐effects resulting in dose limitations and/or cessation of treatment. In this study, we tested whether oxi...

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Detalhes bibliográficos
Publicado no:Br J Pharmacol
Main Authors: McQuade, Rachel M, Carbone, Simona E, Stojanovska, Vanesa, Rahman, Ahmed, Gwynne, Rachel M, Robinson, Ainsley M, Goodman, Craig A, Bornstein, Joel C, Nurgali, Kulmira
Formato: Artigo
Idioma:Inglês
Publicado em: John Wiley and Sons Inc. 2016
Assuntos:
Research Papers
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5120153/
https://ncbi.nlm.nih.gov/pubmed/27714760
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/bph.13646
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